Niaj hnub no, photodamage tau dhau los ua lub ntsiab lus kub, uas tsis yog tsuas yog ua rau tawv nqaij laus thiab cuam tshuam rau cov tsos, tab sis kuj yuav ua rau muaj teeb meem loj. Mid-wave ultraviolet (UVB) yog qhov tseem ceeb hauv kev tsim cov tawv nqaij photodamage. Nws tuaj yeem qhib keratinocytes los tsim cov kab mob inflammatory (xws li IL-1α, PGE2), ua rau erythema, hlwv thiab lwm yam kev raug mob. Pab neeg ntawm Xib Fwb Li Li ntawm Landivine Research Institute tau luam tawm ib txoj kev tshawb fawb nyob rau hauv Tuam Tshoj Science thiab Technology Core Journal "Food thiab Fermentation Industry", qhia thawj zaug uas Ganoderma-Chaga khov-dried hmoov npaj siv cov kua ob-txoj kev fermentation tshuab muaj kev ua tau zoo hauv kev kho UVB lub teeb puas, muab txoj hauv kev tshiab rau kev txhim kho cov khoom siv raw khoom zoo.

Cov ntsiab lus tseem ceeb:

1. Targeted inhibition ntawm inflammatory cua daj cua dub: Ntawm qhov kev nyab xeeb concentration (0.0313 mg / mL), Ganoderma-Chaga (S3) fermentation kua khov-dried hmoov muaj ib qho tseem ceeb inhibitory tus nqi ntawm lub secretion ntawm tseem ceeb inflammatory yam tseem ceeb IL-1α thiab PGE2 los ntawm HaCaT hlwb induced los ntawm UVB, ncaj qha mus tua lub core mechanism ntawm photodamage.
2. Cov nyhuv synergistic yog qhov tseeb: qhov ua tau zoo ntawm Ganoderma-Chaga fermentation ua ke (S3) yog qhov zoo dua li ntawm Ganoderma fermentation ib leeg (S1), tshwj xeeb tshaj yog nyob rau hauv inhibiting muaj zog inflammatory thiab mob ua rau PGE2, cov nyhuv ntawm S3 yog ho muaj zog dua li ntawm S1 (P<0.01).
3. Chaga yog tus tseem ceeb synergist: Los ntawm kev tshawb fawb thiab kev sib piv ntawm tsib fermentation broth freeze-dried hmoov ntawm Ganoderma (S1), Ganoderma-Polygonatum odoratum (S2), Ganoderma-Chaga (S3), Ganoderma-ginseng (S4), thiab Ganoderma-Panax notoginseng tau txiav txim siab tias qhov tseem ceeb (S5), kev txhim kho ntawm Chaga. lub photodamage kho muaj peev xwm ntawm Ganoderma fermentation cov khoom, nthuav tawm lub peev xwm ntawm cov kab mob tshwj xeeb thiab tshuaj sib xyaw ua ke hauv kev tswj hwm metabolic.

IL-1α cov ntsiab lus tshawb pom

Cov nyhuv ntawm S1 ~ S5 ntawm IL-1α cov ntsiab lus zais cia

Cov txiaj ntsig ntawm PGE2

Cov nyhuv ntawm S1 ~ S5 ntawm PGE2 cov ntsiab lus zais cia

Kev tshawb fawb thiab thev naus laus zis tus nqi thiab kev lag luam kev cia siab:

1. Cov txheej txheem tshiab: "Cov tshuaj fungi + cov yam ntxwv cov nroj tsuag" ob-txoj kev fermentation tshuab tuaj yeem ua tiav cov kev hloov pauv thiab ua kom muaj txiaj ntsig ntawm cov khoom xyaw nquag, tawg los ntawm lub raj mis ntawm ib txwm siv Ganoderma raw khoom ua tau zoo.
2. Cov khoom siv zoo tshaj plaws: Cov tau txais S3 khov-qhuav hmoov muaj kev ua haujlwm ruaj khov, cov nyhuv meej meej, thiab muaj kev nyab xeeb lom neeg, uas ua tau raws li qhov kev thov rau cov khoom siv raw hauv high-end los tiv thaiv kev yees duab, tom qab-hnub kho thiab soothing tawv nqaij cov khoom.
3. Lub hauv paus ruaj khov rau kev lag luam: Cov txheej txheem no muaj qhov zoo ntawm cov khoom loj xws li lub voj voog luv luv, cov khoom siv loj, cov nqi tswj tau, thiab cov khoom zoo sib xws, tso lub hauv paus rau kev txhim kho ntawm "fermentation source" tsom rau cov khoom siv los tiv thaiv cov khoom siv raw nrog kev ywj pheej kev txawj ntse txoj cai.

Cov ntsiab lus tshawb fawb:

Txoj kev tshawb no tau ua tiav xaiv Ganoderma-Chaga ob txoj kev fermentation (S3) ua qhov zoo tshaj plaws los tiv thaiv UVB kev puas tsuaj ua ke, thiab lees paub nws cov kev kho kom zoo los ntawm cov qauv ntawm tes. Qhov no tsis tsuas yog muab kev txhawb nqa kev tshawb fawb thiab thev naus laus zis rau kev siv cov txiaj ntsig zoo ntawm Ganoderma thiab Chaga cov peev txheej, tab sis kuj tseem qhib txoj hauv kev tshiab rau kev txhim kho cov tiam tom ntej ntawm cov txiaj ntsig zoo, ntsuab, thiab tsom rau cov khoom xyaw tshuaj pleev ib ce, uas yog qhov tseem ceeb rau kev txhim kho kev lag luam kev sib tw.